Intergenic, gene terminal, and intragenic CpG islands in the human genome

BMC Genomics

Table 1 Ratio of bona fide CGIs-exons (introns) overlap and "simulated" overlap average

Gene region	Bona fide overlap length/Simulated overlap average
	"Simulated" CGIs	"Simulated" exons
3000 bp flank region	14.54	12.6
exon in 5' UTR	66.46	63.33
intron in 5' UTR (5' 200 bp)	30.36	26.49
intron in 5' UTR	2.35	2.2
intron in 5' UTR (3' 200 bp)	24.08	21.07
initial coding exon	39.32	35.4
initial intron in coding area (5' 200 bp)	24.16	21.77
initial intron in coding area	1.76	1.7
initial intron in coding area (3' 200 bp)	20.17	18.05
internal exon	7.15	14.87
internal intron (5' 200 bp)	1.81	3.25
internal intron	0.39	0.78
internal intron (3' 200 bp)	1.55	2.83
terminal coding exon	13.01	11.75
terminal intron in coding area (5' 200 bp)	3.51	3.22
terminal intron in coding area	0.64	0.62
terminal intron in coding area (3' 200 bp)	3.05	2.77
exon in 3' UTR	1.93	1.82
intron in 3' UTR (5' 200 bp)	3.99	3.26
intron in 3' UTR	0.61	2.25
intron in 3' UTR (3' 200 bp)	2.8	0.56

The total length of CGI overlapping with exons and introns in different gene regions normalized for the expectation estimated from overlapping of randomly sampled intervals.

ISSN: 1471-2164