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Table 6 Comparison of the power and proportion of false positives of KWII to RPM.

From: Comparison of information-theoretic to statistical methods for gene-gene interactions in the presence of genetic heterogeneity

K p h 2 Model α Power % RPM PFP*
     KWII RPM  
0.3 0.62 5A 0.001 100 100 0.0010
    0.0001 100 100 0.0002
  0.3 5B 0.001 100 100 0.0018
    0.0001 100 100 0.0004
  0.15 5C 0.001 97.7 93.0 0.0014
    0.0001 90.1 84.2 0.0003
0.1 0.22 6A 0.001 100 100 0.0011
    0.0001 100 100 0.0002
  0.11 6B 0.001 100 100 0.0014
    0.0001 100 100 0.0004
  0.056 6C 0.001 86.6 75.2 0.0013
    0.0001 73.6 56.5 0.0002
0.01 0.02 7A 0.001 100 100 0.0010
    0.0001 100 100 0.0002
  0.01 7B 0.001 99.3 98.4 0.0013
    0.0001 98.4 95.8 0.0003
  0.005 7C 0.001 72.6 58.4 0.0016
    0.0001 51.6 40.5 0.0005
  1. * α is calibrated to the empirical false positive rate of KWII
  2. The simulations are based on the models in [2].