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Table 1 Enrichment analysis in GO of transcripts from alternate exon usage and differential expression analysis of lymphocyte proliferation.

From: Implementation of exon arrays: alternative splicing during T-cell proliferation as determined by whole genome analysis

Analysis Compare to D0 No. significant transcript Cell cycle process Cell cycle Cell division Metabolic process Chromosome segregation Cellular organization and biogenesis Cell proliferation Cell death Cell adhesion Cell communication
No. genes in category 376 381 234 3599 25 924 278 417 620 527
  D1 204           
  D3 359     108     20   
AEU D5 288 13   9 80   26     
  D7 256 11    75   24     
  Time 472     121   39     
  D1 621   30   161    17 25   
  D3 1855 116 119 80 499 12 137 57 66 35 34
DE D5 880 76 84 61 207 11 68 33 30   
  D7 818 66 68 52 196 10 64 32 32   
  Time 1980 120 116 82 518 13 153 53 68   39
  1. Gene Ontology (GO) enrichment analysis of transcript lists was undertaken in Partek Genomic Suite. Results are presented for Cellular Process category under the GO Biological Process. Groups are presented with an enrichment score > 3 and > 5 genes per group.
  2. AEU: alternate exon usage
  3. DE: Differential expression
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BMC Genomics

ISSN: 1471-2164

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