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Table 2 List of the 18 genes that have different expression patterns in BMS- and BMS+FA-treated embryos.

From: Hif1α down-regulation is associated with transposition of great arteries in mice treated with a retinoic acid antagonist

Gene symbol

Gene name

FC

BMS/untreated controls

FC BMS+FA/BMS

GO classification

Tfpi

tissue factor pathway inhibitor

-1.79

+1.18

coagulation

Mgp

Matrix Gla protein

+1.73

-2. 77

cell differentiation

Rragb

Ras-related GTP binding B

-1.589

+1.11

signal transduction

Hs3st6

heparan sulphate (glucosamine) 3-O-sulfotransferase 6

-1.55

+1.40

heparan sulphate synthesis

B2m

beta-2 microglobulin

-1.71

+1.28

immune response

Hif1α

hypoxia inducible factor 1, alpha subunit

-1.79

+1.17

cardiac looping

Rpn2

ribophorin II

+1.78

-1.59

protein glycosylation

Rhoj

ras homolog gene family, member J

-1.67

+1.30

signal transduction

Spcs2

signal peptidase complex subunit 2 homolog (S. cerevisiae)

+1.70

1.38

signal peptide processing

Atp6v1b1

ATPase, H+ transporting, lysosomal V1 subunit B1

+2.08

1.01

proton transport

Lmbrd2

LMBR1 domain containing 2

-1.88

+1.16

unknown biological process

Rnf217

ring finger protein 217

+2.05

-1.26

unknown biological process

Vmn2r52

vomeronasal 2, receptor 52

-1.67

+1.26

transmembrane receptor

D14Abb1e

DNA segment, Chr 14, Abbott 1 expressed

-1.70

+1.38

unknown

XM_981869

 

+1.78

-1.75

unknown

XM_991521

 

+1.55

-1.24

unknown

XM_994830

 

-2.37

+1.13

unknown

NM_133970

 

-1.51

+1.40

unknown

  1. Genes in bold have been analysed by qRT-PCR.