From: Unravelling the neurophysiological basis of aggression in a fish model
Region of brain | GenBank accession no. | Gene | Description | Pathway | Fold-increase in dominants (mean ± SEM) | P-value |
---|---|---|---|---|---|---|
Genes overexpressed in dominants | ||||||
Hypothalamus | NM_178293 | avpl | arginine vasopressin-like | HNS | 3.89 ± 0.82 | 0.014 |
 | XM_695195 | avplr1b | arginine vasopressin-like receptor 1b | HNS | 3.04 ± 0.82 | 0.022 |
 | NM_178291 | oxtl | oxytocin-like | HNS | 3.19 ± 0.58 | 0.016 |
 | NM_214795 | tph2 | tryptophan hydroxylase 2 | 5-HT | 2.83 ± 0.46 | 0.005 |
 | EH441641 | htr1a | 5-hydroxytryptamine (serotonin) receptor 1A | 5-HT | 2.89 ± 0.72 | 0.037 |
 | DQ285098 | slc6a4a | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4a | 5-HT | 3.44 ± 0.57 | 0.001 |
 | NM_212827 | maoa | monoamine oxidase a | 5-HT | 3.52 ± 0.82 | 0.014 |
 | AF435965 | sst1 | somatostatin 1 | Somatostatin | 1.77 ± 0.28 | 0.042 |
 | BI473045 | sst3 | somatostatin 3 | Somatostatin | 3.61 ± 1.00 | 0.002 |
 | AF075384 | th | tyrosine hydroxylase | Dopamine | 2.10 ± 0.40 | 0.038 |
 | NM_131755 | slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | Dopamine | 2.56 ± 0.56 | 0.030 |
 | NM_001045338 | hrh2 | histamine receptor h2 | Histamine | 1.96 ± 0.30 | 0.029 |
 | NM_131660 | nos1 | nitric oxide synthase 1 (neuronal) | Nitric oxide | 2.51 ± 0.51 | 0.022 |
 | NM_001007379 | crh | corticotropin releasing hormone | HPI | 1.88 ± 0.29 | 0.025 |
 | EF567112 | nr3c1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | HPI | 2.02 ± 0.38 | 0.040 |
 | NM_131074 | npy | neuropeptide y | HPI | 4.37 ± 0.95 | 0.002 |
 | AJ304429 | gnrh3 | gonadotropin-releasing hormone 3 | HPG | 2.78 ± 0.67 | 0.044 |
 | NM_131642 | cyp19a1b | cytochrome P450, family 19, subfamily A, polypeptide 1b | HPG | 2.95 ± 0.57 | 0.001 |
 | AB037185 | esr1 | estrogen receptor 1 | HPG | 3.02 ± 0.80 | 0.005 |
 | NM_180966 | esr2a | estrogen receptor 2a | HPG | 2.80 ± 0.55 | 0.022 |
 | NM_001083123 | ar | androgen receptor | HPG | 2.61 ± 0.52 | 0.014 |
Telencephalon | XM_695195 | avplr1b | arginine vasopressin-like receptor 1b | HNS | 1.80 ± 0.22 | 0.031 |
 | AF548566 | tph1a | tryptophan hydroxylase 1a | 5-HT | 4.61 ± 0.74 | 0.001 |
 | NM_214795 | tph2 | tryptophan hydroxylase 2 | 5-HT | 3.09 ± 0.55 | 0.016 |
 | BI473045 | sst3 | somatostatin 3 | Somatostatin | 1.92 ± 0.33 | 0.029 |
 | NM_131755 | slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | Dopamine | 2.48 ± 0.48 | 0.017 |
 | AJ304429 | gnrh3 | gonadotropin-releasing hormone 3 | HPG | 1.87 ± 0.35 | 0.048 |
 | AJ414566 | esr2b | estrogen receptor 2b | HPG | 1.79 ± 0.27 | 0.029 |