Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites

Table 2 Point mutations common to both AS-30CQ and AS-15MF.

Chr	Ref. seq. (AS-WTSI)	AS-sens	AS-30CQ and AS-15MF	Gene ID	Substitution	Gene abbreviation	Annotation
2	C	C	A	PCHAS_020720	V2728F	*ubp1*	de-ubiquitinating enzyme
7	G	G	A	PCHAS_072830	S106N	*dhfr*	dihydrofolate reductase
11	G	G	T	-	non-synonymous	-	-
14	T	T	G	-	intergenic	-	-

ISSN: 1471-2164