Normal colon epithelium: a dataset for the analysis of gene expression and alternative splicing events in colon disease

Table 2 Alternatively spliced genes in a comparison of tumors and isolated epithelial cells.

# Probesets	Transcript ID	Gene Symbol	RefSeq	Alternative Splicing p-value	Fold Change Tumor vs Cell
13	3959350	APOL3	NM_030644	7.20E-11	-1.0483
14	3079463	ABCF2	NM_007189	2.53E-16	-1.0105
14	3082759	DLGAP2	NM_004745	0.0102642	-1.75766
20	3859761	DMKN	NM_033317	1.72E-25	-1.00705
33	3132016	FGFR1	NM_023111	0	1.86159
17	4026722	IDH3G	NM_174869	3.34E-21	1.37367
12	4027708	MTCP1	NM_001018025	0.000139499	-1.12104
22	2628785	MITF	NM_006722	1.62E-27	1.04061
23	3795184	NFATC1	NM_172389	1.05E-19	1.03091
54	3564071	NIN	NM_020921	7.07E-13	1.03063
35	2517588	OSBPL6	NM_032523	2.44E-10	-1.26328
40	2858134	PDE4D	NM_006203	0	-1.69311
29	3923632	PFKL	NM_001002021	0	1.258
12	3751184	PHF12	NM_001033561	8.89E-18	1.09533
19	3821200	PRKCSH	NM_001001329	0	-1.0575
9	3688311	PYCARD	NM_145182	2.36E-10	1.58277
38	2395245	RERE	NM_012102	0	-1.10969
38	2683763	ROBO1	NM_002941	0	2.52196
25	3930360	RUNX1	NM_001754	0	2.48266
14	4007588	SLC35A2	NM_001042498	3.63E-08	-1.01314
23	2428313	ST7L	NM_138729	1.59E-42	-1.26644
18	3049025	TBRG4	NM_199122	0.00E+00	2.29256
21	2402601	UBXD5	NM_183008	3.82E-14	1.00668
12	2706791	ZMAT3	NM_152240	1.02E-19	1.5543

The genes were selected by limiting the p-values for alternative splicing to <.0001. To eliminate genes that had whole transcript level differences the p value for gene expression was set at p > 0.9 and a fold change of <2.5 or >-2.5. The individual probesets for the genes were then visually examined and those with corresponding reports of alternative splicing events in RefSeq were included in the analysis.

ISSN: 1471-2164