Table 3 Representative genes significantly differentially expressed after A. hydrophila infection
Gene Name | Accession NO. | Describe | Fold | P value |
|---|---|---|---|---|
Immunity related genes | ||||
TLR1 | P79800 | Toll-like receptor 1 | 18/0 | 0.000001 |
TLR2 | NM_212812 | Toll-like receptor 2 | 0/94 | 0 |
TLR3 | BAD01045 | Toll-like receptor 3 | 4/0 | 0 |
TLR22 | NM_001128675 | Toll-like receptor 22 | -2.5 | 0 |
IL-1β | gb|AAP33156.1| | Interleukin-1β | +17.9 | 0 |
IL-8 | XP_695462 | Interleukin-8 | +20.8 | 0.000007 |
IL-2rgb | NM_001123050 | Interleukin 2 receptor, gamma b | +2.3 | 0.001956 |
IL-4r | NM_001013282 | Interleukin 4 receptor | +1.4 | 0.000015 |
IL-6r | NM_001114318 | Interleukin 6 receptor | +2.2 | 0.000023 |
CCL-4 | CAO78735.1 | CC chemokine ligand 4 | +2.75 | 0 |
CCL-c25v | NM_001115103 | Chemokine CCL-C25v | 0/34 | 0 |
CCr-1 | ref|NP_001028030.1 | CC chemokine receptor type 1 | +9.6 | 0 |
CCr-12.3 | NM_001045027 | CC chemokine receptor family-like | +4.4 | 0 |
Crlf-3 | ref|NP_001167401.1 | cytokine receptor-like factor 3 | 65/0 | 0 |
TNFaip8 | NM_200332 | TNF, alpha-induced protein 8-like protein 1 | -2.2 | 0.043671 |
TNFsf10l2 | NM_001002593 | TNF superfamily, member 10 like 2 | -1.3 | 0.00616 |
Jfmip1a | dbj|BAC10650.1| | MIP1alpha | -2.5 | 0.000505 |
Cklr | gb|AAP58737.1| | C-type lectin receptor | +1.7 | 0 |
Blnk | NM_212838 | B-cell linker | -1.6 | 0 |
zgc:55347 | NM_213522 | Immunoglobulin binding protein 1 | 4/0 | 0.026366 |
Fcgr1 | gb|ACN10126.1| | High affinity immunoglobulin gammaFc receptor I precursor | +2.6 | 0.049003 |
CD3g/d | ref|NP_001033072.1 | CD3 gamma/delta | -1.9 | 0 |
Rad23b | NM_200564 | RAD23 homolog B | +2.4 | 0.018151 |
Fas | ref|NP_001075464. | Fas | 4/0 | 0.026366 |
Casp9 | NM_001007404 | caspase9 apoptosis-related cysteine protease | +5.8 | 0.000013 |
Was | emb|CAQ15295.1| | Wiskott-Aldrich syndrome | -3.3 | 0.017699 |
Tpsn | NM_130974 | Tapasin | +2.3 | 0 |
Lipf | NM_213404 | Lipf protein | +2.4 | 0 |
Hsp90a.1 | NM_131328 | Heat shock protein HSP 90-alpha 1 | +1.2 | 0.048885 |
Gadd45al | NM_200576 | Growth arrest and DNA-damage-inducible, beta | +1.7 | 0 |
Prdx1 | NM_001013471 | Peroxiredoxin 1 | +5.8 | 0 |
Prdx2 | NM_001002468 | Peroxiredoxin 2 | -1.5 | 0 |
Glrx5 | NM_213021 | Glutaredoxin 5 | +1.3 | 0.015063 |
Gpx1b | NM_001004634 | Glutathione peroxidase 1b | +1.4 | 0 |
Gpx4b | NM_001030070 | Glutathione peroxidase 4b | -1.4 | 0 |
zgc:85657 | NM_214749 | Non-homologous end-joining factor 1 | -1.4 | 0.02618 |
Mpx | NM_212779 | Myeloid-specific peroxidase | -1.9 | 0.02238 |
Ube2nl | NM_200342 | Ubiquitin-conjugating enzyme E2N-like | +2 | 0 |
Transcription regulator activity | ||||
NF-kB2 | NM_001001840 | NF-kB, p49/p100 | -1.7 | 0 |
NF-kBie | NM_001080089 | NF-kB 2 inhibitor, epsilon | +1.7 | 0 |
Jak1 | NM_131073 | Janus kinase 1 | +6.1 | 0.003023 |
Stat1 | ref|NP_001117126.1| | STAT1 alpha | +3.9 | 0.027891 |
Jun | NM_199987 | c-Jun | 0/5 | 0.02144 |
Jund | NM_001128342 | Jun D proto-oncogene | +1.5 | 0.012807 |
Xbp1 | NM_131874 | X-box binding protein 1 | 0/6 | 0.011301 |
Smad9 | NM_001004014 | Smad9 | -3.6 | 0.031597 |
Slp-1 | gb|AAC41262.1| | Transcription factor | 0/4 | 0.040678 |
Srf | gb|AAH50480.1| | Srf protein | -1.5 | 0.006007 |
Tp53 | NM_131327 | Cellular tumor antigen p53 | -1.2 | 0.031928 |
Cebpa | NM_131885 | CCAAT/enhancer binding protein alpha | 11/0 | 0.00014 |
Pdlim1 | NM_001017870 | PDZ and LIM domain 1 | +2.1 | 0.000003 |
Ahr2b | ref|NP_001033052.1| | Aryl hydrocarbon receptor 2B | +2.3 | 0.00573 |
IRF | dbj|BAA83468.1| | interferon regulatory factor | +2.9 | 0 |
IRF4 | NM_001122710 | interferon regulatory factor 4 | +1.2 | 0.040115 |
IRF9 | NM_205710 | interferon regulatory factor 9 | +2.3 | 0 |
Max | NM_131220 | Myc-associated factor X | +1.3 | 0.003228 |
Rargb | NM_001083310 | Retinoic acid receptor gamma | 13/0 | 0.000031 |
Ldb1a | NM_131313 | LIM domain-binding protein 4 | +1.6 | 0.0016 |
Cse1l | NM_201450 | Chromosome segregation 1-like | -1.2 | 0.045136 |
Ppp1r10 | NM_212568 | protein phosphatase 1, regulatory subunit 10 | -1.2 | 0.00723 |
Ppp1caa | NM_214811 | protein phosphatase 1, catalytic subunit alpha | -3.9 | 0.007564 |
Gtf2h2 | NM_201581 | General transcription factor IIH, polypeptide 2 | 4/0 | 0.026366 |
Gtf2h3 | NM_001002564 | General transcription factor IIH, polypeptide 3 | +2.5 | 0.000295 |
Gf2f2 | NM_001017832 | General transcription factor IIF, polypeptide 2 | +1.4 | 0.021645 |
Gtf2e2 | NM_212731 | General transcription factor IIE, polypeptide 2, beta | +31.9 | 0 |