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Table 2 List of 17 transcription factor families from ENCODE (UCSC genome web browser) and other published sources, and their detailed methylation profiles in hearts and sperm.

From: Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated

Motif family

Heart

Sperm

E2F1

Hypo-methylated

Hypo-methylated

NFY1

Hypo-methylated

Hypo-methylated

YY11

Hypo-methylated

Hypo-methylated

MYCMAX1

Hypo-methylated

Hyper-methylated

NFKB1

Hypo-methylated

Hyper-methylated

AP1

Hypo-methylated

Hyper-methylated

NRSF2

Hypo-methylated

Neutral

SREBP3

Hypo-methylated

Neutral

SRF2

Hypo-methylated

Neutral

STAT4

Hypo-methylated

Neutral

TCF1

Hypo-methylated

Neutral

GATA1

Neutral

Hyper-methylated

NFE21

Neutral

Neutral

OCT5

Neutral

Neutral

SOX5

Neutral

Neutral

EP3005

Neutral

Neutral

TP536

Neutral

Neutral

  1. 1Yale/UCD/Harvard (ENCODE)
  2. 2HudsonAlpha Institute
  3. 3Yale/UCD/Harvard/Duke UNC/UT, Genome Institute of Singapore (GIS)
  4. 4Yale/UCD/Harvard, GIS
  5. 5Lister et al, Nature 2009
  6. 6GIS