Table 5 Stem cell signaling pathway genes in OS epithelial regions

WNT signalling pathway

NM_016269

LEF1

(1.2)

-

-

NM_006261

CDH1

(5.3)

-

(-5.8)

NM_013263

BRD7

(-4.0)

(1.8)

(4.0)

NM_001892

CSNK1A1

-

(4.6)

-

AF267864

TBL1XR1

-

-

(1.9)

NM_003507

FZD7

-

-

(2.0)

NM_022825

PORCN

-

-

(2.0)

NM_018890

RAC1

(-3.0)

-

(3.0)

NM_001320

CSNK2B

(-2.6)

-

(2.6)

NM_014248

RBX1

(5.6)

(-5.6)

Notch Signalling pathway

NM_014276

RBPJL

(-3.9)

-

(3.9)

NM_005524

HES1

(-1.5)

-

(2.1)

NM_203283

RBPJ

-

-

(4.6)

NM_033632

FBXW7

(-6.1)

-

(6.1)

JAK/STAT Signalling pathway

NM_004232

SOCS6

-

-

(3.9)

U52912

LEPR

(-3.4)

(-2.2)

(3.4)

U52914

LEPR

-

-

(2.3)

AJ271736

IL9R

-

(-4.2)

(4.2)

NM_000565

IL6R

-

(-8.7)

(8.7)

NM_003150

STAT3

-

-

(1.7)

NM_000297

PKD2

(-2.8)

-

(2.8)

NM_014432

IL20RA

(-4.2)

-

(4.2)

TGF-Beta Signalling pathways

NM_002165

ID1

(-3.6)

(1.5)

(3.6)

NM_006350

FST

-

-

(2.4)

NM_014248

RBX1

(5.6)

-

(-5.6)

NM_002165

ID1

(-3.6)

(1.5)

(3.6)

BMP Signalling pathway

AL096865

RUNX2

(-2.4)

-

(2.4)

NM_006350

FST

-

-

(2.4)

Hedgehog signalling pathway (HH)

NM_001892

CSNK1A1

-

(4.5)

-

NM_016004

IFT52

-

(2.5)

-

NM_005870

SAP18

(-5.3)

(-3.7)

(6.2)