Table 6 Relative fold change in genes differentially expressed in human hepatocellular adenoma (HCA), rat HCA and the hepatic gene expression profiles of rats exposed to TCDD, PCB126, and PCB153 p.o. for 52 weeks

NM_053401

Ngfrap1

Nerve growth factor receptor (TNFRSF16) associated protein 1

NGFRAP1

N/C

13

8

6

N/C

NM_012752

Cd24

CD24 antigen

CD24

10

N/C

7

4

N/C

NM_017127

Chka

Choline kinase alpha

CHKA

2

N/C

5

6

N/C

NM_057104

Enpp2

Ectonucleotide pyrophosphatase/phosphodiesterase 2

ENPP2

4

N/C

4

5

N/C

NM_017166

Stmn1

Stathmin 1

STMN1

2

N/C

4

N/C

2

NM_145878

Fabp5

Fatty acid binding protein 5, epidermal

FABP5

2

N/C

4

3

N/C

NM_022298

Tuba1

Tubulin, alpha 1

TUBA4A

N/C

11

3

N/C

N/C

NM_053515

Slc25a4

Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4

SLC25A4

N/C

8

3

N/C

N/C

NM_012862

Mgp

Matrix Gla protein

MGP

4

N/C

3

3

N/C

NM_012946

Sparcl1

SPARC-like 1 (mast9, hevin)

SPARCL1

3

N/C

2

2

N/C

NM_030987

Gnb1

Guanine nucleotide binding protein, beta 1

GNB1

2

N/C

N/C

3

N/C

NM_031795

Ugcg

UDP-glucose ceramide glucosyltransferase

UGCG

2

N/C

N/C

N/C

2

NM_023103

Mug1

Murinoglobulin 1 homolog (mouse)

none

N/C

-5

-2

N/C

N/C

NM_134432

Agt

Angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

AGT

N/C

-5

-2

N/C

N/C

NM_012899

Alad

Aminolevulinate, delta-, dehydratase

ALAD

-2

N/C

-2

-3

N/C

NM_053770

Argbp2

Arg/Abl-interacting protein ArgBP2

ARGBP2

-3

N/C

-2

N/C

N/C

NM_022508

Mthfd1

Methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase

MTHFD1

-5

N/C

-2

N/C

N/C

NM_012716

Slc16a1

Solute carrier family 16 (monocarboxylic acid transporters), member 1

SLC16A1

-3

N/C

-2

N/C

N/C

NM_013177

Got2

Glutamate oxaloacetate transaminase 2, mitochondrial

GOT2

-2

N/C

N/C

N/C

-2

NM_012737

Apoa4

Apolipoprotein A-IV

APOA4

N/C

-9

-3

-4

N/C

NM_053923

Pik3c2g

Phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide

PIK3C2G

-3

N/C

-3

-3

N/C

NM_024484

Alas1

Aminolevulinic acid synthase 1

ALAS1

-3

N/C

-3

-3

2

NM_019185

Gata6

GATA binding protein 6

GATA6

-3

N/C

-3

-4

N/C

NM_053328

Bhlhb2

Basic helix-loop-helix domain containing, class B2

BHLHB2

-2

N/C

-4

N/C

N/C

XM_001076124///XM_001076147///XM_001076171///XM_341825

Prodh2

Proline dehydrogenase (oxidase) 2

PRODH2

-3

N/C

N/C

-3

N/C

NM_147206

Cyp3a13

Cytochrome P450, family 3, subfamily a, polypeptide 13

CYP3A4

N/C

-9

-606

-610

N/C