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Table 2 Up-regulation of genes in iBMDCs treated with [BF/S+L/Ep] for (A) 4 h or (B) 12 h compared to DMSO alone

From: Stimulatory effect of Echinacea purpurea extract on the trafficking activity of mouse dendritic cells: revealed by genomic and proteomic analyses

 

Gene Name

Accession Number

Expression Ratioa(+)/(-)

At 4 h:

   

   Cluster 1

Adhesion molecules, Cytoskeleton, Cell movement

  

   Ncam2

neural cell adhesion molecule 2

NM_010954

6.57

   Serpinb2

serine (or cysteine) peptidase inhibitor, clade B, member 2

NM_011111

4.50

   Ikbkg

inhibitor of kappa B kinase gamma

NM_010547

2.03

   Cluster 2

Immune response

  

   Amot

angiomotin

NM_153319

2.48

   Cxcl5

chemokine (C-X-C motif) ligand 5

NM_009141

8.63

   Irg1

immunoresponsive gene 1

XM_127883

2.17

   Cxcl7

chemokine (C-X-C motif) ligand 7

NM_023785

2.08

   Cluster 3

Signal transmission, Transporter

  

   Nrxn1

neurexin I

Q9CS84

9.62

   Sorbs1

sorbin and SH3 domain containing 1

NM_009166

3.70

   Ahrr

aryl-hydrocarbon receptor repressor

NM_009644

2.37

   Abce1

ATP-binding cassette, sub-family E (OABP), member 1

NM_015751

2.10

   Cluster 4

Cell cycle, DNA repair, Apoptosis

  

   Cyr61

cysteine rich protein 61

NM_010516

6.60

   Mtap9

microtubule-associated protein 9

Q3TRR0

2.64

   Cluster 5

Enzyme, Kinase

  

   Ppfia1

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF)

XM_133979

2.74

   Cluster 6

DNA binding protein, Transcription factor

  

   Wdhd1

WD-repeat HMG-box DNA binding protein 1

NM_172598

2.04

   Cluster 7

Miscellaneous

  

   Prdm10

PR domain containing 10

Q3UTQ7

6.98

   Tdrd3

Tudor domain containing 3

NM_172605

3.48

   Mif4gd

MIF4G domain containing

NM_027162

2.16

   Dnahc2

dynein, axonemal, heavy chain 2

O08826

2.09

At 12 h:

   

   Cluster 1

Adhesion molecules, Cytoskeleton, Cell movement

  

   Serpinb2

serine (or cysteine) peptidase inhibitor, clade B, member 2

NM_011111

3.34

   Cspg2

chondroitin sulfate proteoglycan 2

NM_019389

2.20

   Mmp8

matrix metallopeptidase 8

NM_008611

2.18

   Myo1d

Myosin ID

NM_177390

2.07

   Cluster 2

Signal transmission, Transporter

  

   Phip

pleckstrin homology domain interacting protein

Q32NY1

3.28

   Cd38

CD38 antigen

NM_007646

2.51

   Rbp1

retinol binding protein 1, cellular

NM_011254

2.28

   Ap3s2

adaptor-related protein complex 3, sigma 2 subunit

NM_009682

2.12

   Golph4

golgi phosphoprotein 4

NM_175193

2.03

   Cluster 3

Enzyme, Kinase

  

   Dnm1l

dynamin 1-like

NM_152816

13.11

   Wdfy3

WD repeat and FYVE domain containing 3

NM_172882

4.64

   Acpp

acid phosphatase, prostate

NM_019807

2.18

   Apc

adenomatosis polyposis coli

NM_007462

2.15

   Adhfe1

alcohol dehydrogenase, iron containing, 1

NM_175236

2.04

   Cluster 4

Immune response

  

   Ctla4

cytotoxic T-lymphocyte-associated protein 4

NM_009843

11.16

   Cxcl7

chemokine (C-X-C motif) ligand 7

NM_023785

2.77

   Cluster 5

RNA binding protein, Translation factor

  

   Mrps5

mitochondrial ribosomal protein S5

NM_029963

2.20

   Sf4

splicing factor 4

NM_027481

2.45

   Cluster 6

DNA binding protein, Transcription factor

  

   Asb2

ankyrin repeat and SOCS box-containing protein 2

NM_023049

2.75

   Cluster 7

Miscellaneous

  

   Dnahc2

dynein, axonemal, heavy chain 2

O08826

3.11

   Ccdc89

coiled-coil domain containing 89

Q9DA73

2.01

  1. a Expression ratio is defined as relative difference in expression with (+) compared to without (-) treatment with [BF/S+L/Ep] plant extract; (-) is DMSO vehicle control.
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BMC Genomics

ISSN: 1471-2164

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