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Table 3 Down-regulation of genes in iBMDCs treated with [BF/S+L/Ep] for (A) 4 h or (B) 12 h compared to DMSO alone

From: Stimulatory effect of Echinacea purpurea extract on the trafficking activity of mouse dendritic cells: revealed by genomic and proteomic analyses

  Gene Title Accession Number Expression Ratioa(+)/(-)
At 4 h:    
   Cluster 1 Adhesion molecules, Cytoskeleton, Cell movement   
   Cnn3 calponin 3, acidic NM_028044 0.13
   Cdh10 cadherin 10 Q3UUB3 0.27
   Itga6 Integrin alpha 6 NM_008397 0.50
   Cluster 2 Cell cycle, DNA repair, Apoptosis   
   Sycp1 synaptonemal complex protein 1 NM_011516 0.25
   Cluster 3 Enzyme, Kinase   
   Atad1 ATPase family, AAA domain containing 1 NM_026487 0.48
   St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-
sialyltransferase 6
NM_145838 0.45
   Prkce Protein kinase C, epsilon NM_011104 0.47
   Cluster 4 DNA binding protein, Transcription factor   
   Shprh SNF2 histone linker PHD RING helicase NM_172937 0.27
   Zfp39 zinc finger protein 39 NM_011758 0.31
   Cluster 5 Miscellaneous   
   Cep110 centrosomal protein 110 XM_981952 0.46
At 12 h:    
   Cluster 1 Adhesion molecules, cytoskeleton; cell movement   
   Cdh1 Cadherin 1 NM_009864 0.30
   Gja1 gap junction membrane channel protein alpha 1 NM_010288 0.48
   Cluster 2 Signal transmission, Transporter   
   Rab17 RAB17, member RAS oncogene family NM_008998 0.42
   Oscar osteoclast associated receptor NM_175632 0.44
   Kcne3 Voltage-gated potassium channel, Isk-related subfamily, gene 3 NM_020574 0.49
   Sla src-like adaptor NM_009192 0.50
   Cluster 3 Enzyme, Kinase   
   Setd4 SET domain containing 4 NM_145482 0.32
   Ndufb2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 NM_026612 0.39
   Acss1 acyl-CoA synthetase short-chain family member 1 NM_080575 0.40
   Cluster 4 DNA binding protein, Transcription factor   
   Sox6 SRY-box containing gene 6 NM_011445 0.06
   Dmc1h disrupted meiotic cDNA 1 homolog NM_010059 0.17
   Nfxl1 nuclear transcription factor, X-box binding-like 1 Q3ULV1 0.36
   Huwe1 HECT, UBA and WWE domain containing 1 NM_021523 0.41
   Cluster 5 Protein metastasis   
   Fbxo36 F-box only protein 36 NM_025386 0.46
   Cluster 6 RNA binding protein, Translation factor   
   Rbm14 RNA binding motif protein 14 NM_019869 0.50
   Cluster 7 Miscellaneous   
   Speer4b spermatogenesis associated glutamate (E)-rich protein 4b NM_028561 0.19
   Ccdc21 coiled-coil domain containing 21 NM_144527 0.47
   Mgl1 macrophage galactose N-acetyl-galactosamine specific lectin 1 NM_010796 0.48
  1. a Expression ratio is defined as relative difference in expression with (+) compared to without (-) treatment with [BF/S+L/Ep] plant extract; (-) is DMSO vehicle control.