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Table 4 Differentially expressed proteins identified by MALDI-TOF-MS/MS analysis of 2D gel protein profiles of iBMDCs treated with [BF/S+L/Ep] (75 ug/mL) in vitro for 12 h

From: Stimulatory effect of Echinacea purpurea extract on the trafficking activity of mouse dendritic cells: revealed by genomic and proteomic analyses

Spot Number

Protein Name

Relative Protein Levela

SwissProt Accession Number

Biological Function

54

Annexin A4

1.73

P97429

Signal transduction; cell communication

34

Peroxiredoxin 4

1.56

O08807

Metabolism; Energy pathways

82

Vimentin

1.13

P20152

Cell growth/maintenance

26

Alpha-actin-2

1.12

P62739

Cell growth/maintenance

23

Proliferin-1

1.1

P04095

Cell growth/maintenance

98

APAF1-interacting protein

1.09

Q9WVQ5

apoptosis

1

beta-actin

1.05

P99041

Cell growth/maintenance

58

Alpha-tubulin 1, 2, 4, 6

1.04

P68369...

Cell growth/maintenance

79

Heat shock cognate 71 kDa protein

1.04

P63017

Protein metabolism

109

Solute carrier family 35 member E1

1.04

Q8CD26

Transport

55

Actin, cytoplasmic 1 (Beta-actin)

1.03

P60710

Cell growth/maintenance

88

YEATS domain-containing protein 4

0.96

Q9CR11

Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism

6

Phenylalanyl-tRNA synthetase

0.92

Q99M01

Protein metabolism

41

Protein disulfide-isomerase A3 [Precursor]

0.92

P27773

Protein metabolism

38

Phosphoglycerate mutase 1

0.87

Q9DBJ1

Metabolism; Energy pathways

78

Heat shock protein 9, [Precursor]

0.84

P38647

Protein metabolism

56

F-actin capping protein alpha subunit

0.83

P47754

Cell growth/maintenance

13

Cathepsin S

0.81

O70370

Protein metabolism

91

Nucleoside diphosphate kinase

0.74

Q9WV84

Metabolism; Energy pathways

70

Alpha-enolase

0.73

P17182

Metabolism; Energy pathways

45

Macrophage capping protein

0.63

P24452

Cell growth/maintenance

192

Voltage-gated potassium channel subfamily KQT member 2

0.46

Q9Z351

Transport

191

Protein tyrosine phosphatase mitochondrial 1

0.34

Q66GT5

signal transduction; cell communication

  1. a Relative protein level with or without [BF/S+L/Ep] (75 μg/mL), 0.1% DMSO as vehicle control.