IPA network depicting relationships among pro-inflammatory genes in cluster 3, 6 hours post-infestation with P. ovis. Individual nodes represent protein functions with relationships represented by edges. Nodes coloured by gene expression, red indicating up-regulation and white indicating gene/factor not differentially expressed but with defined relationship to other genes in network. Arrows indicate directional relationships. Red circles highlight roles for NF-kB, IFNGR1 and IFNGR2. Network score = 38.