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Table 2 Features of different PCS classes in human

From: Imprinted genes show unique patterns of sequence conservation

group number of PCSs conser-vation score length (bp) G+C content PCSs with ≥ 1 CpG CpGobs/CpGexp of PCSs with ≥ 1 CpG (TpG+CpA)/(2·CpG) ratio of PCSs with ≥ 1 CpG
overlapping with CpG islands
imprinted 321 392 69 65.93% 94.38% 0.79 0.73
maternal 170 417 75 66.48% 95.29% 0.85a 0.59
paternal 151 379 62 65.44% 92.72% 0.74* 0.83*
autosomal 55931 385 58 67.48% 95.30% 0.83 0.68
intronic
imprinted 1120 320* 40 38.89%**** 32.05%*** 0.51**** 2.50*****
maternal 719 320 41 39.39%**** 33.38%*** 0.52** 2.50*****
paternal 401 320 40 38.10%** 29.68% 0.50** 2.50****
autosomal 365258 329 40 36.54% 25.42% 0.42 3.83
intergenic
imprinted 1787 325**** 40**** 39.04%***** 33.97%*** 0.47**** 2.83*****
maternal 832 320**** 39*** 35.78%c 25.00%b 0.53****a 3.00****
paternal 955 329*** 41 42.31%*** 41.78%*** 0.45* 2.50*****
autosomal 588309 338 43 36.36% 27.32% 0.42 4.00
unique
imprinted 2357 325**** 39**** 38.46%***** 29.87%*** 0.45**** 3.00*****
maternal 1304 320***** 39**** 36.72%c 25.61%b 0.46**** 3.00*****
paternal 1053 329*** 40 40.74%***** 35.14%*** 0.44 3.00*****
autosomal 844703 338 42 36.36% 25.49% 0.39 4.33
  1. * p < 0.01, ** p < 0.005, *** p < 0.001, **** p < 1e-4, ***** p < 1e-10 for comparison with autosomal PCSs (χ2 test for fractions of PCSs, Wilcoxon test for all other features). If maternally and paternally expressed genes differ significantly from each other, this is indicated as following: a p < 0.05, b p < 0.005, c p < 1e-4
  2. Unique PCSs do not overlap with protein encoding exons, repetitive elements, or CpG islands. The shown absolute numbers of PCSs are not normalized by the lengths of the analyzed genomic segments. Hence they give information about the amount of available data but not about frequencies or coverage of PCSs in the listed genomic segments.