Figure 1
From: Re-examination of chimp protein kinases suggests "novel architectures" are gene prediction artifacts
Alignment of ENSPTRP00000001150 with PLK3 from human (RefSeq NP_004064.2), exon structure from human, and chimp Whole Genome Shotgun reads from the NCBI trace archive corresponding to segments homologous to human PLK3 but missing from ENSPTRP00000001150. Asterisks mark remaining amino acid changes between human and chimp PLK3 if all of the additional information is incorporated. Exons implied by chimp whole genome shotgun traces (NCBI Trace Archive entries 231320434, 240048640 and 236037896) are also shown. The kinase domain of human PLK3 is highlighted in yellow, with the key ATP binding region underlined.