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Table 1 Phase variable gene candidates in H. canadensis strain NCTC 13241.

From: Simple sequence repeats in Helicobacter canadensis and their role in phase variable expression and C-terminal sequence switching

Tract *

Range†

Candidacy ‡

Location

Locus

Description

(G)10

(G)8 - 11

strong

within gene

HCAN_0054

hypothetical protein, frame-shifted

(G)14

(G)11 - 17

possible promoter

promoter

HCAN_0075

hypothetical

(G)11

(G)9 - 14

good

within gene

HCAN_0101

glycosyl transferase

(G)9

(G)8 - 10

strong

within gene

HCAN_0115

acetyl-coenzyme A synthetase 2, frame-shifted

(G)13

(G)11 - 15

strong

within gene

HCAN_0151

hypothetical protein, frame-shifted

(G)12

(G)9 - 14

strong

within gene

HCAN_0153

polysaccharide deacetylase family protein, frame-shifted

(A)12

(A)10 - 14

possible promoter

promoter

HCAN_0162

conserved hypothetical

(G)14

(G)12 - 16

possible promoter

promoter

HCAN_0234

immunoglobulin A1 protease precursor

(G)14

(G)11 - 16

putative

within gene ¶

HCAN_0344

putative filamentous haemagglutinin domain protein

(G)14

(G)10 - 16

good

within gene

HCAN_0346

conserved hypothetical protein

(G)16

(G)12 - 20

possible promoter

promoter

HCAN_0457

vacuolating cytotoxin precursor

(G)14

(G)11 - 16

good

within gene

HCAN_0632

putative oxidoreductase

(G)11

(G)9 - 12

good

within gene

HCAN_0647

putative methyltransferase

(G)12

(G)10 - 14

strong

within gene

HCAN_0648

conserved hypothetical protein, frame-shifted

(G)11

(G)10 - 12

good

within gene

HCAN_0651

conserved hypothetical protein

(G)11

(G)9 - 13

good

within gene

HCAN_0655

hypothetical protein

(G)9

(G)7 - 11

putative

within gene

HCAN_0659

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

(G)11

(G)9 - 12

good

within gene

HCAN_0670

hypothetical protein

(G)13

(G)11 - 14

strong

within gene

HCAN_0671

methyltransferase, frame-shifted

(G)13

(G)10 - 14

possible promoter

promoter

HCAN_0714

vacuolating cytotoxin precursor

(G)13

(G)10 - 14

good

within gene

HCAN_1335

conserved hypothetical protein

  1. * Tract length from accession number CM000776 [32].
  2. † Range is the range of repeat copy number observed in the sequence read data (see Additional Files files 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 and 21).
  3. ‡ Candidacy is based on the presence of a frame-shift and the length of the repeat tract.
  4. ¶This would be a strong candidate for phase variation if an alternative initiation codon 5' of the repeat was chosen rather than that annotated.