Promoter histogram scores. Histograms of scores from (a) ARTS, and (b) Profisi on 519 dbTSS promoters and 2,595 non-promoters drawn from the ENCODE regions. ARTS scores are the output of an SVM, while Profisi scores are DNA melting temperatures. Promoters are black and non-promoters are grey. Specificity is high at high thresholds, but many promoters are given low scores, and are obscured by non-promoters.