Figure 10

Biological effects in colon mucosa with Salmonella infection. A. Expression of Akt protein with or without Salmonella infection at 4 days post-infection. B. Distribution of Akt in normal or infected mouse colon at 4 days post-infection. C. Representative pathological aspects of colon section in the control, the 8 hour post-infection group, and the 4 day post infection group. Please note that Salmonella induce inflammatory features at 4 days post-infection. D. Salmonella distribution in mouse colon 4 days post-infection Salmonella shown in bright green in the mouse mucosa by using immuno-staining assay. E. BrdU labeling of small intestine epithelial cells showed Salmonella increase colon intestinal epithelial cell proliferation in vivo. The number of BrdU-positive cells per three high powered fields was counted. n = 3 in each experimental group.