Table 2 Genome sequencing and metabolic SNP detection
Sequencing Parameter | S288c | CEN.PK113-7D |
|---|---|---|
MAQ Software Determination | ||
No. of Reads | 5,301,907 | 6,603,200 |
Total No. of SNPs | 3,032 | 27,868 |
Total No. of Non-Ambiguous SNPs | 1,013 | 24,663 |
Total No. of Filtered SNPs A,B | 311 | 13,787 |
Metabolism Focused Detection | ||
Total No. of Metabolic Genes Considered C | 782 | 782 |
Total No. of Metabolic Bases (bp) | 1.16M | 1.16M |
No. of Aligned Reads | 477,565 | 623,400 |
Total Gap Size (bp) | 0 | 0 |
Metabolic Genome Percent Reference Coverage (%) | 99.7 | 99.4 |
Total No. of Metabolic SNPs detected | 36 | 939 |
Total No. Nonsynonymous Metabolic SNPs Detected | 3 | 219 |
Percent of SNPs Detected Nonsynonymous (%) | 8.3 | 23.3 |
Total No. of Metabolic Genes Containing SNP | 14 | 158 |
Total No. of Metabolic Genes with Nonsynonymous SNP | 3 | 85 |