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Figure 8 | BMC Genomics

Figure 8

From: Analysis of deep sequencing microRNA expression profile from human embryonic stem cells derived mesenchymal stem cells reveals possible role of let-7 microRNA family in downstream targeting of Hepatic Nuclear Factor 4 Alpha

Figure 8

HNF4A is a common hub for networks derived from alignment data and TargetScan predictions. Gene interaction network on the left (A) is derived from the dataset of genes with overlapping regions corresponding to peaks from previous mapping. The other gene interaction networks (B) is derived from computationally predicted gene targets from TargetScan. Comparing both gene interaction network, similar topology was observed with HNF4A as a node amongst the interactions suggesting HNF4A as a possible downstream target for let-7 family miRNAs.

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