Table 1 Effect of window sizes on sequence-based prediction of protein stability changes.
From: Sequence feature-based prediction of protein stability changes upon amino acid substitutions
Window size | AC (%) | SN (%) | SP (%) | ST (%) | MCC | ROC AUC |
|---|---|---|---|---|---|---|
1 | 66.92 | 70.69 | 65.20 | 67.94 | 0.3349 | 0.7425 |
3 | 73.91 | 74.83 | 73.49 | 74.16 | 0.4554 | 0.7996 |
5 | 77.51 | 76.67 | 77.90 | 77.28 | 0.5194 | 0.8512 |
7 | 80.80 | 76.43 | 82.83 | 79.63 | 0.5750 | 0.8737 |
9 | 81.28 | 75.66 | 83.78 | 79.72 | 0.5774 | 0.8755 |
11 | 81.82 | 74.48 | 85.11 | 79.79 | 0.5843 | 0.8804 |
13 | 82.10 | 71.84 | 86.67 | 79.26 | 0.5824 | 0.8797 |
15 | 81.45 | 69.71 | 86.75 | 78.23 | 0.5665 | 0.8775 |
17 | 81.88 | 69.50 | 87.58 | 78.54 | 0.5779 | 0.8799 |
19 | 81.21 | 68.80 | 86.98 | 77.89 | 0.5627 | 0.8779 |
21 | 81.29 | 68.98 | 86.98 | 77.98 | 0.5645 | 0.8735 |