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Table 2 Predictive performance of classifiers constructed using single sequence features.

From: Sequence feature-based prediction of protein stability changes upon amino acid substitutions

Features AC
(%)
SN
(%)
SP
(%)
ST
(%)
MCC ROC
AUC
H 75.88 71.62 77.79 74.70 0.4728 0.8237
K 73.29 73.90 73.02 73.46 0.4402 0.7925
M 68.06 73.52 65.62 69.57 0.3629 0.7480
P 75.94 71.24 78.04 74.64 0.4718 0.8234
Co 70.18 71.62 69.53 70.58 0.3838 0.7586
A 76.41 74.29 77.36 75.82 0.4904 0.8206
B 78.18 74.48 79.83 77.15 0.5199 0.8503
C 72.18 71.05 72.68 71.86 0.4116 0.7847
Aa 79.12 76.57 80.26 78.41 0.5431 0.8459
Bu 82.06 75.62 84.94 80.28 0.5919 0.8777
S1 69.82 70.86 69.36 70.11 0.3756 0.7754
S2 70.24 72.19 69.36 70.78 0.3875 0.7665
S3 82.53 72.19 87.15 79.67 0.5922 0.8835
F 61.41 63.62 60.43 62.02 0.2226 0.6728
R 66.47 65.14 67.06 66.10 0.3008 0.7140
Mc 78.35 73.52 80.51 77.02 0.5202 0.8417
No 69.82 74.86 67.57 71.22 0.3944 0.7656
Rf 62.06 73.71 56.85 65.28 0.2831 0.6889
Rm 75.94 69.90 78.64 74.27 0.4672 0.8118
Tt 83.59 66.48 91.23 78.86 0.6035 0.8704