Figure 1
From: The interplay between evolution, regulation and tissue specificity in the Human Hereditary Diseasome
Distribution of transcription factors and proteins that undergo post-translational modification across the phylostrata. Proportion of transcription factors (TF; red profile) and post-translational modifiers (PTM; black profile) originating at each of the 19 phylostrata. Horizontal red and black lines correspond to the bounds of the 95% confidence interval for TF and PTM, respectively, and based on the entire set of 12,753 genes.