Figure 4

The evolution of tissues based on gene expression across different tissues . Genes expressed in each of the 32 tissues are recorded and plotted are the proportion of old genes (upper left panel; old defined as phylostrata 1 or 2), proportion of disease genes (upper right panel), proportion of other tissues where the genes are also expressed (bottom left panel) and the proportion of regulator genes (bottom right panel). Their identity and percentage of genes they expressed (out of 7,111) are as follows: 1. Pancreas (23.7%); 2. Kidney (41.6%); 3. Pituitary gland (49.8%); 4. Cerebellum (48.1%); 5. Fetal brain (50.3%); 6. Adrenal gland (50.4%); 7. Amygdala (56.4%); 8. Heart (48.0%); 9. Brain caudate nucleus (53.8%); 10. Peripheral blood lymphocytes (38.1%); 11. Thalamus (54.4%); 12. Spinal cord (57.0%); 13. Uterus (58.8%); 14. Brain corpus callosum (55.7%); 15. Placenta (37.5%); 16. Colon (35.3%); 17. Stomach (34.8%); 18. Monocytes (40.4%); 19. Hypothalamus (54.3%); 20. Prostate (46.0%); 21. Bladder (48.3%); 22. Salivary gland (36.9%); 23. Thyroid (54.8%); 24. Small intestine (57.3%); 25. Trachea (54.0%); 26. Retina (55.0%); 27. Mammary gland (48.5%); 28. Thymus (56.6%); 29. Bone marrow (41.9%); 30. Testis (65.1%); 31. Spleen (56.9%); 32. Lung (55.1%).