Table 2 Summary of the significant relationships between the gene attributes.
From: The interplay between evolution, regulation and tissue specificity in the Human Hereditary Diseasome
Disease | Age | PTMs | Tissue Specificity | Interactions |
|---|---|---|---|---|
When compared to non-disease genes a higher proportion of Disease genes are Interacting (20) • PTM (13) • Long (13) • Old (8) | When compared to New genes a higher proportion of Old genes are • Long (27) • House Keeping genes (16) • Interacting (14) • PTM (6) | When compared to proteins that carry no PTM a higher proportion of Protein that harbour PTMs are • Interacting (23) • Long (15) • Expressed at high levels (7) • House keeping genes (6) | When compared to proteins that carry no PTM a higher proportion of Protein that harbour PTMs are • Interacting (23) • Long (15) • Expressed at high levels (7) • House keeping genes (6) | When compared to non-interacting genes a higher proportion of Interacting are • Long (12) • Expressed at high levels (10) • Transcription factors (7) |