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Table 4 Examples of SOX2 regulated genes and families

From: The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis

Gene Symbol

ratio SOX2 _KO/MOCK

Description

SOX family

  

SOX1

0.32

SRY (sex determining region Y)-box 1

SOX18

0.50

SRY (sex determining region Y)-box 18

SOX2

0.30

SRY (sex determining region Y)-box 2

Brain-expressed

 

BASP1

3.52

brain abundant, membrane attached signal protein 1

BEX2

3.29

brain expressed X-linked 2

BEX1

4.81

brain expressed, X-linked 1

G protein-coupled receptor

 

GPR1

4.22

G protein-coupled receptor 1

GPR172B

2.07

G protein-coupled receptor 172B

GPR37

0.49

G protein-coupled receptor 37

Interleukins and their receptors

 

IL1RL1

2.48

interleukin 1 receptor-like 1

IL23A

2.60

interleukin 23, alpha subunit p19

IL24

5.73

interleukin 24

IL32

2.42

interleukin 32

IL6

10.25

interleukin 6 (interferon, beta 2)

IL7R

2.32

interleukin 7 receptor

IL8

2.22

interleukin 8

Solute carrier family

 

SLC14A1

4.81

solute carrier family 14 (urea transporter), member 1 (Kidd blood group)

SLC2A3

2.29

solute carrier family 2 (facilitated glucose transporter), member 3

SLC22A1

3.80

solute carrier family 22 (organic cation transporter), member 1

SLC3A2

2.07

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

SLC30A1

2.62

solute carrier family 30 (zinc transporter), member 1

SLC7A1

2.25

solute carrier family 7 (cationic amino acid transporter, y+ system), member 1

Protocadherin family

 

PCDH10

0.45

protocadherin 10

PCDH9

0.32

protocadherin 9

PCDHA4

2.20

protocadherin alpha 4

PCDHB11

0.38

protocadherin beta 11

PCDHGA3

0.49

protocadherin gamma subfamily A, 3

PCDHGC3

0.43

protocadherin gamma subfamily C, 3

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BMC Genomics

ISSN: 1471-2164

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