Mesenteric lymph node transcriptome profiles in BALB/c mice sensitized to three common food allergens

BMC Genomics

Table 1 List of common top 10 up-regulated and top 10 down-regulated genes significantly (p < 0.05) differentially expressed in BALB/c mice in response to BLG, OVA and PNA sensitizations.

			BLG		OVA		PNA
Unigene ID	Gene Symbol	Gene Name	Fold Change	P-Value	Fold Change	P-Value	Fold Change	P-Value
Mm.8245	Timp1	Tissue inhibitor of metalloproteinase 1	9.8	4E-03	18.4	2E-03	13.4	1E-02
Mm.259609	Prrg4	Proline rich Gla (G-carboxyglutamic acid) 4	3.5	3E-04	7.6	8E-03	4.7	1E-02
Mm.289645	Meg3	Maternally expressed 3	4.7	1E-03	4.2	1E-02	8.3	1E-02
Mm.646	Tpm2	Tropomyosin 2, beta	3.8	4E-05	2.6	4E-04	2.9	3E-04
Mm.295533	Flna	Filamin, alpha	3.2	3E-05	2.6	2E-04	2.4	8E-04
Mm.22701	Gas1	Growth arrest specific 1	3.2	2E-04	2.6	3E-04	2.1	7E-03
Mm.26700	Tmem16a	Transmembrane protein 16A	5.3	4E-03	2.5	3E-04	3.5	4E-03
Mm.12459	Ankrd10	Ankyrin repeat domain 10	3.5	4E-03	2.2	3E-03	2.6	7E-03
Mm.196110	Hba-a1	Hemoglobin alpha, adult chain 1	3.6	2E-03	2.2	5E-03	2.8	4E-03
Mm.20954	Rgs5	Regulator of G-protein signalling 5	2.8	9E-06	2.2	2E-04	2.5	2E-03
Mm.431947	Ovgp1	Oviductal glycoprotein 1	-4.4	4E-05	-4.6	1E-03	-3.0	2E-03
Mm.33401	Mgam	Maltase-glucoamylase	-5.5	6E-08	-4.6	2E-08	-9.2	6E-06
Mm.1641	Car4	Carbonic anhydrase 4	-3.6	1E-04	-4.7	6E-04	-8.0	7E-06
Mm.4533	Apoa4	Apolipoprotein A-IV	-11.2	5E-06	-5.3	2E-08	-19.1	8E-06
Mm.1186	Car2	Carbonic anhydrase 2	-1.5	1E-02	-6.0	2E-03	-5.2	7E-06
Mm.210336	Lgals4	Lectin, galactose binding, soluble 4	-11.2	8E-07	-7.2	2E-05	-5.0	3E-05
Mm.7244	Agr2	Anterior gradient 2	-5.5	3E-10	-9.7	9E-07	-13.9	7E-07
Mm.297976	Gpc1	Glypican 1	-4.9	7E-08	-10.7	3E-12	-7.3	1E-05
Mm.273195	Car1	Carbonic anhydrase 1	-5.4	8E-08	-12.6	2E-10	-8.2	9E-06
Mm.11869	AI427122	Expressed sequence AI427122	-8.3	4E-07	-13.2	2E-08	-8.5	2E-06

ISSN: 1471-2164