Alteration of gene expression by alcohol exposure at early neurulation

BMC Genomics

Table 3 Genes in Experiment 2 that are turned on or off by alcohol treatment.

Gene Symbol	Genbank	p-value	Change in Alcohol-treated	Description
Alc-NTC
Add2*	NM_013458	0.0196	Off	Adducin 2 (beta)
B2m*	NM_009735	0.0446	Off	Beta-2 microglobulin
Cfi	NM_007686	0.0494	Off	Complement component factor i
Cp*	NM_007752	0.0225	Off	Ceruloplasmin
Fbxo2	NM_176848	0.0290	Off	F-box only protein 2
Gch1	NM_008102	0.0017	Off	GTP cyclohydrolase 1
Gfi1b	NM_008114	0.0007	Off	Growth factor independent 1B
Nppb	NM_008726	0.0103	Off	Natriuretic peptide precursor type B
Pitpnm1	NM_008851	0.0272	Off	Phosphatidylinositol membrane-associated 1
Ppgb	NM_008906	0.0044	Off	Protective protein for beta-Galactosidase
Tacr2	NM_009314	0.0108	Off	Tachykinin receptor 2
ALC-NTO
Acbd5	NM_028793	0.0292	Off	Acyl-Coenzyme A binding domain containing 5
B2m*	NM_009735	0.0446	Off	Beta-2 microglobulin
Fbxo2	NM_176848	0.0290	Off	F-box only protein 2
Frmd3	NM_172869	0.0004	Off	FERM domain containing 3
Gypa*	NM_010369	0.00001	Off	Glycophorin A
Mlr1	BB298201	0.0295	Off	Mblk1-related protein-1
Ogn	NM_008760	0.0363	Off	Osteoglycin
Pdcd4	BG230003	0.0468	Off	Programmed cell death 4
Sqstm1	NM_011018	0.0357	Off	Sequestosome 1
Aldh1b1	NM_028270	0.0048	On	Aldehyde dehydrogenase 1 family, member B1

Off = present in ≥ 75% of arrays in control and in no arrays of alcohol-treated samples.
On = not present in any control, present in ≥ 75% of arrays from alcohol-treated.
Only named genes are shown. * = hematopoiesis gene.
P-value: as compared with Control.

ISSN: 1471-2164