Table 4 GSEA for Early Developmental Biology GO sets.
From: Alteration of gene expression by alcohol exposure at early neurulation
Comparison | Keyword | Gene Set | Gene Set Description | Size | p-value Exp. 2 | Significant Genes | p-value Exp. 1 |
|---|---|---|---|---|---|---|---|
Control vs ALC-NTO/ALC-NTC (see legends) | Growth, Growth Regulation* | GO:0016049 GO:0040007 | ^Cell growth ^Growth | 47 75 | 0.002 0.005 | (Ctgf, Igfbp2, Emp1, Osm, Cyr61, Gap43, Crim1, Tgfb3, Igfbp7, Nov, Emp3), Gpc3, Csf1, Socs2, Bmp6, Bmp4, Inhbb, Lepre1, Wrn, Wig1, Cish | 0.010 0.010 |
| Â | Â | GO:0001558 GO:0040008 | Regulation of cell growth Regulation of growth | 39 56 | 0.002 0.016 | (Ctgf, Igfbp2, Osm, Cyr61, Gap43, Crim1, Igfbp7, Nov), Gpc3, Csf1, Socs2, | 0.006 0.017 |
| Â | Â | GO:0005520 | Insulin-like growth factor binding | 14 | 0.000 | Ctgf, Igfbp2, Cyr61, Crim1, Igfbp7, Nov | 0.012 |
| Â | Heart* | GO:0001525 | Angiogenesis | 53 | 0.022 | Ctgf, Anxa2, Cyr61, Thbs1, Vegfa, Tie1, Elk3, Flt1, Crhr2, Vegfc, Kdr, Bmp4, Adra2b, Tnfrsf12a | 0.022 |
| Â | Eye# | GO:0001654 | Eye Development | 26 | 0.040 | Mab21l1, Neurod1, Neurod4, Ntrk2, Fkbp8, Bmpr1b, Crb1, Stat3, Tspan5, Pax6, Bmp4, Map3k1 | 0.004 |
| Â | Epigenetic factor~,^ | GO:0006334 | Nucleosome modeling | 30 | 0.021 | Hist3h2b, a; Hist1h3f; Hist1h1c; Hist1h2b, c; Hist1h3a; H1f0; Smarca2; Nap1l3 | 0.033 |
ALC-NTO vs ALC-NTC | Growth, Growth retardation | GO:0007173 | Epidermal growth factor receptor (EGFR) signaling pathway | 5 | 0.019 | Pde6g, Egfr, Hbegf (Enriched in ALC-NTC) | 0.023 |