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Table 5 GSEA for Stem Cell Related Gene Sets

From: Alteration of gene expression by alcohol exposure at early neurulation

Comparison

Gene Set

Size

p-value

Exp. 2

Significant Genes

p-value

Exp. 1

Control vs ALC

Other ECM Molecules~^

9

0.002

Ctgf, Thbs2, Tgfbi, Ecm1

0.016

 

ECM Protease Inhibitors~,#

7

0.004

Thbs1, Timp3

0.006

 

TGF-β Activin-responsiv~ e

16

0.010

Junb, Fos, Tgfbi, Pdgfb, Tgfb1i1, Igf1

0.014

 

Other Regulators of Cell Differentiation (Neural Specification) #

17

0.003

Elavl3, Neurod1, Neurod4, Nhlh1, Neurog1, Nhlh2, Neurog3, Spock2, Neurog2

0.004

 

Other Related growth Factor^

Other Related growth Factor#

7

0.005

0.040

Ctgf, Igf1

Ctgf Hgf Igf1

0.015

0.008

  1. ~= Gene set is reduced in ALC (all alcohol group) as compared with Control.
  2. ^= Gene set is reduced in ALC-NTO as compared with Control.
  3. #= Gene set is reduced in ALC-NTC as compared with Control.
  4. ECM: extracellular matrix