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Table 3 Significant KEGG identifiers detected based on the differentially expressed genes between three studies of E. col i infection in the bovine udder*

From: In depth analysis of genes and pathways of the mammary gland involved in the pathogenesis of bovine Escherichia coli- mastitis

KEGG ID P value Odds Ratio Exp Count Count Size Term
4062 6.05E-08 6.785196 2.70837 15 106 Chemokine signaling pathway
4670 1.73E-06 7.273962 1.839648 11 72 Leukocyte transendothelial migration
4650 1.02E-05 7.646809 1.430837 9 56 Natural killer cell mediated cytotoxicity
4620 5.14E-05 7.058635 1.354185 8 53 Toll-like receptor signaling pathway
4060 0.00053 4.306462 2.350661 9 92 Cytokine-cytokine receptor interaction
4622 0.001365 6.982249 0.843172 5 33 RIG-I-like receptor signaling pathway
4514 0.002293 4.237402 1.839648 7 72 Cell adhesion molecules (CAMs)
4662 0.00231 6.105769 0.945374 5 37 B cell receptor signaling pathway
4920 0.003278 5.579882 1.022026 5 40 Adipocytokine signaling pathway
4210 0.01013 4.147677 1.328634 5 52 Apoptosis
4666 0.011834 3.977177 1.379736 5 54 Fc gamma R-mediated phagocytosis
4610 0.025259 3.88 1.124229 4 44 Complement and coagulation cascades
561 0.027695 5.044241 0.664317 3 26 Glycerolipid metabolism
4142 0.038281 2.85764 1.865198 5 73 Lysosome
4630 0.040239 2.815796 1.890749 5 74 Jak-STAT signaling pathway
  1. *A hypergeometric gene set enrichment test was performed based on overlapping genes between the study described in this paper, Mitterhuemer et al. [14], and Rinaldi et al. [15]. Overrepresentation of gene sets defined by the KEGG database was tested using the Fisher's exact test. A gene set was considered significant if P < 0.05.