Within-tissue correlation of eigengene transcript abundance profiles. The eigengenes of the adipose-green and adipose-magenta modules exhibit negative within-mouse correlation and positive between-mouse correlation (rw = -0.65, rb = 0.69) Profiles are shown for (A) Ccl6 (l) and Ccl9 (r) of the positively correlated adipose-green module and KEGG cytokine-cytokine receptor interaction pathway, (B) Cd8b1 (l) and Elf1 (r) of the positively correlated adipose-magenta module and GO immune response biological process, and (C) Lep (l) and Trp53inp2 (r), of the negatively correlated adipose-magenta module. The graphical features of the eigengene plots of Figure 4 apply to these gene plots. Profiles are coloured by module membership. Summary statistics for these genes are available [Additional file 10: Supplemental Table S3].