Figure 2

Gene set enrichment analysis results for the translation category. The translation category is enriched by up regulated genes in heart (A, false discovery rate (FDR) of <0.001) and liver (B, FDR = 0.046) of hibernating black bears. An expression data set sorted by correlation with hibernating phenotype and the corresponding heat map with red for up regulated and blue for down regulated genes during hibernation are shown on the left. Dates on the top indicate time of tissue sampling from each bear. Plot of the running sum for enrichment score (ES) in the data set (top) and location of genes (hits) from each GO category in the list ranked according to expression differences (middle) and the ranked list metric (bottom) are shown on the right.