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Table 1 Gene expression differences tested by microarray and real-time PCR in bear heart and liver

From: Modulation of gene expression in heart and liver of hibernating black bears (Ursus americanus)

Gene Symbol

Gene Name

RT-PCR

Microarray

  

P

log2FC

P

log2FC

HEART

    

Acadvl

Acyl-Coenzyme A dehydrogenase, very long chain

0.034

0.122

<0.001

0.747

Dnajc8

DnaJ (Hsp40) homolog, subfamily C, member 8

0.008

0.270

<0.001

0.698

Gapdh

Glyceraldehyde-3-phosphate dehydrogenase

0.140

n/a

0.008

0.620

Mbip

MAP3K12 binding inhibitory protein 1

0.580

n/a

0.001

0.884

Rbm3

RNA binding motif protein 3

<0.001

2.349

<0.001

2.863

Rpl35a

Ribosomal protein L35a

0.009

0.550

<0.001

1.857

Rpl7

Ribosomal protein L7

0.004

0.533

<0.001

1.243

Rps27

Ribosomal protein S27

0.009

0.600

0.001

0.720

Adk

Adenosine kinase

0.015

-0.164

0.006

-0.534

Aldh6a1

Aldehyde dehydrogenase 6 family, member A1

<0.001

-0.974

0.001

-0.893

Ank1

Ankyrin 1, erythrocytic

<0.001

-1.234

<0.001

-1.440

Gstz1

Glutathione transferase zeta 1

0.031

-0.343

0.001

-0.605

Ube2v1

Ubiquitin-conjugating enzyme E2 variant 1

0.001

-0.327

0.004

-0.600

LIVER

    

Gpc3

Glypican 3

<0.001

2.307

<0.001

1.965

Rplp2

60S acidic ribosomal protein P2

<0.001

1.378

0.003

1.627

Cmtm8

CKLF-like MARVEL transmembrane domain-containing protein 8

0.170

n/a

<0.001

1.525

Pc

Pyruvate carboxylase

0.130

n/a

0.002

1.390

Crip2

Cysteine-rich protein 2

<0.001

1.064

0.001

1.285

A2m

Alpha 2 macroglobulin

0.003

1.287

0.004

1.249

Rpl36

60S ribosomal protein L36

0.002

0.963

0.004

1.223

Brp44l

Brain protein 44-like protein

0.002

1.638

0.009

1.198

Naca

Nascent-polypeptide-associated complex alpha polypeptide variant

<0.001

0.714

0.001

1.182

Fgfr2

Fibroblast growth factor receptor 2 precursor

<0.001

1.055

<0.001

1.130

Tbca

Tubulin cofactor a

0.001

0.579

0.001

1.122

Rps6

Ribosomal protein S6

0.001

0.677

0.010

1.079

Comt

Catechol-O-methyltransferase

<0.001

-0.741

0.001

-1.817

Arg1

Arginase

0.016

-1.418

0.009

-2.050

Phyh

Phytanoyl-CoA 2-hydroxylase

0.002

-1.328

0.004

-2.105

Tinag

Tubulointerstitial nephritis antigen

<0.001

-1.822

<0.001

-2.141

Ugt3a2

UDP glycosyltransferase 3 family, polypeptide A2

<0.001

-4.034

<0.001

-2.949

Fmo5

Flavin-containing monooxygenase 5

0.001

-2.631

0.002

-3.002

Pitrm1

Pitrilysin metalloprotease 1

0.027

-0.421

0.001

-3.360

  1. Inconsistent significance levels for some genes are in bold.
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BMC Genomics

ISSN: 1471-2164

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