Skip to main content

Table 1 Summary of biological responses of TK6 cells exposed to arsenic or cadmium

From: Comparative genomic analyses identify common molecular pathways modulated upon exposure to low doses of arsenic and cadmium

 

Arsenic (0.1 μM)

Cadmium (0.1 μM)

Percent Survival

99%

99%

Genes Differentially Expressed (probesets)

62 (74)

105 (135)

Gene Set Enrichment

(FWER)

Cancer Module 88

(Liver, heart, lung) (0.33)

Cancer Module 88

(Liver, heart, lung) (0.49)

 

Cancer Module 55

(Liver, lung, breast) (0.33)

Cancer Module 55

(Liver, lung, breast) (0.49)

  

Cancer Module 23

(Liver, lung, prostate) (0.49)

  

Cancer Module 6

(Lung, prostate, liver) (0.34)

Transcription Factor Binding Site Enrichment (p-value)

RBP-Jkappa (0.001)

ZF5 (0.002)

 

Oct-1 (0.002)

Sp1 (0.011)

 

E2F (0.015)

SREBP-1 (0.016)