Table 10 Age-regulated adipocyte gene expression
From: Characterization of age-related gene expression profiling in bone marrow and epididymal adipocytes
| Â | Â | Bone marrow | Epididymal | Â | ||
|---|---|---|---|---|---|---|
Symbol | Entrez Gene Name | 14M | 18M | 14M | 18M | p -value (Age) |
TRIB2 | tribbles homolog 2 (Drosophila) | 3.0 | 1.2 | 1.8 | -1.2 | 1.78E-05 |
TNFα | tumor necrosis factor α | 2.4 | -1.5 | -2.4 | -2.2 | 0.00013 |
IRS2 | insulin receptor substrate 2 | 2.0 | -1.1 | -4.3 | -2.9 | 0.00018 |
EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 1.8 | 1.2 | 1.7 | 1.5 | 2.12E-06 |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 1.4 | -2.1 | -3.8 | -5.6 | 4.87E-07 |
PPARGC1α | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 1.4 | -1.1 | -1.0 | 2.0 | 0.0024 |
IL1β | interleukin 1, beta | 1.4 | -1.5 | -2.3 | -2.2 | 0.00026 |
FN1 | fibronectin 1 | 1.4 | -1.2 | 7.1 | -3.2 | 4.20E-07 |
PARP2 | poly (ADP-ribose) polymerase 2 | 1.4 | 1.2 | 1.3 | 1.2 | 0.0018 |
CCND1 | cyclin D1 | 1.3 | 1.1 | 2.5 | -1.6 | 0.00062 |
INSIG1 | insulin induced gene 1 | 1.3 | 1.5 | 1.3 | 2.8 | 0.0057 |
FGF10 | fibroblast growth factor 10 | 1.2 | 1.2 | -2.6 | 1.0 | 0.0031 |
DDIT3 | DNA-damage-inducible transcript 3 | 1.2 | -2.1 | -1.8 | -1.2 | 0.0036 |
C3 | complement component 3 | 1.0 | -1.4 | 2.1 | -1.3 | 0.00052 |
PNPLA2 | patatin-like phospholipase domain containing 2 | -1.0 | -1.6 | -1.4 | -1.2 | 0.0049 |
ABHD5 | αβ hydrolase domain containing 5 | -1.0 | -1.4 | -2.0 | -1.1 | 0.00059 |
GPR109A | G protein-coupled receptor 109A | -1.2 | -4.5 | -10.6 | -2.7 | 2.68E-08 |
RARα | retinoic acid receptor, alpha | -1.3 | -2.4 | 1.1 | -1.5 | 3.42E-05 |
RETNLα | resistin like alpha | -1.3 | -1.1 | 3.0 | -10.8 | 8.46E-08 |
ARL4A | ADP-ribosylation factor-like 4A | -1.3 | 1.3 | -2.0 | 1.0 | 3.30E-05 |
EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | -1.4 | -1.6 | -1.6 | -1.2 | 0.0024 |
LAMA4 | laminin, alpha 4 | -1.4 | -1.4 | -1.4 | -1.2 | 0.0065 |
C/EBPα | CCAAT/enhancer binding protein, alpha | -1.5 | -1.4 | -1.3 | 1.1 | 0.0062 |
FABP4 | fatty acid binding protein 4, adipocyte | -1.5 | -2.6 | -1.2 | -1.3 | 0.0026 |
AR | androgen receptor | -1.8 | -2.0 | -1.5 | -1.8 | 0.00026 |
LEP | leptin | -2.0 | -1.8 | 1.0 | 1.6 | 0.0017 |
IL6 | interleukin 6 | -2.0 | -2.1 | -20.5 | -5.6 | 8.65E-07 |