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Table 2 Gene ontologies with differentially expressed genes in bone marrow adipocytes

From: Characterization of age-related gene expression profiling in bone marrow and epididymal adipocytes

Functional Group

Enrichment Score*

P value**

% genes in group present

Biological process

4.39

0.01

18.10

   Cellular

40.9

<0.001

21.9

   Immune system

18.36

<0.001

31.7

   Metabolic

16.67

<0.001

20.7

   Oxidation reduction

37.36

<0.001

30.52

   Lipid

23.63

<0.001

34.7

   Carbohydrate

7.41

<0.001

28.05

   Developmental

4.3

0.01

19.71

   Adipocyte differentiation

18.3

<0.001

47.27

Brown

31.44

<0.001

74.07

White

8.46

<0.001

71.43

Cellular component

3.55

0.03

17.97

Molecular component

1.80

0.17

17.91

  1. A selection of genes generated from ANOVA analysis was assigned to biologically meaningful gene ontology (GO) categories using GO enrichment analysis (Partek® Genome Suite software, version 6.3). Listed are groups of gene-associated biological processes in bone marrow adipocytes compared with epididymal adipocytes (fold change cut off is 2.0). *A high value of enrichment score indicates that the functional group is over-represented in the gene list. **P value is the -log p-value of a Chi-square test.
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BMC Genomics

ISSN: 1471-2164

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