Table 8 Top regulated adipocyte genes in bone marrow adipocytes with age
From: Characterization of age-related gene expression profiling in bone marrow and epididymal adipocytes
Symbol | Entrez Gene Name | 14M | 18M | p-value (cell type*age) |
|---|---|---|---|---|
TNFα | tumor necrosis factor α | 2.37 | -1.38 | 1.47E-05 |
FOXO1 | forkhead box O1 | 1.99 | 1.17 | 0.0006 |
IRS2 | insulin receptor substrate 2 | 1.93 | -1.08 | 0.0008 |
C/EBPβ | CCAAT/enhancer binding protein beta | 1.79 | -1.23 | 1.22E-05 |
CD36 | fatty acid translocase | 1.38 | 2.00 | 0.001 |
PPARγ | peroxisome proliferator-activated receptor gamma | 1.36 | 1.08 | 0.003 |
PLIN3 | perilipin 3, TIP47 | 1.25 | 1.04 | 0.007 |
SOD2 | superoxide dismutase 2, mitochondrial | 1.24 | -1.09 | 0.001 |
UCP2 | uncoupling protein 2 | 1.24 | 1.18 | 8.1E-06 |
LIPE | lipase, hormone sensitive | 1.23 | -1.27 | 2.1E-05 |
SERPINE1 | plasminogen activator inhibitor type 1 | 1.21 | -1.30 | 0.0004 |
GPX1 | glutathione peroxidase 1 | 1.04 | 1.23 | 0.0002 |
SLC2A4 | GLUT-4 | -1.11 | 1.30 | 0.04 |
CFD | adipsin | -1.12 | 1.25 | 0.002 |
FABP4 | fatty acid binding protein 4, adipocyte | -1.52 | -2.46 | 0.001 |
PTPN11 | protein tyrosine11 | -1.58 | -1.21 | 0.0006 |
ADIPOR2 | adiponectin receptor 2 | -1.66 | -1.44 | 0.001 |
LEPR | leptin receptor | -1.94 | 1.44 | 0.002 |
IL6 | interleukin 6 (interferon, beta 2) | -2.19 | -1.91 | 8.34E-05 |
ADIPOQ | adiponectin | -2.25 | -1.88 | 0.01 |