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Table 2 Combination of experiments and time points to create the 4 main responses to mastitis infection

From: Strengthening insights into host responses to mastitis infection in ruminants by combining heterogeneous microarray data sources

 

Time after infection

Experiment #

2 h

3 h

6 h

8 h

12 h

24 h

36 h-72 h

72 h

1A: E. coli in cattle (in vivo)

  

{1}

I, II, IV

 

{2}

I, IV

{3}

I, III, IV

  

1B: S. aureus in cattle (in vivo)

  

{4}

I, IV

 

{5}

I, IV

{6}

I, II, IV

  

1C: S. aureus in cattle (in vivo)

    

{7}

I, II, IV

  

{8}

I, III, IV

2: S. uberis in cattle (in vivo)

      

{9}

I, IV

 

3: S. aureus in cattle macrophages (in vitro)

{10}

I, II, IV

 

{11}

I, III, IV

     

4: S. aureus in goat (in vivo)

    

{12}

I, II

{13}

I, III

  

5: S. aureus in sheep dendritic cells (in vitro)

 

{14}

I, II

 

{15}

I, III

    

6: S. aureus in goat (in vivo)

     

{16}

I

  
  1. Combination of microarray data from a total of 6 different experiments and 16 different time points ({in parentheses}, see also Table 1 and text for details) to analyse 4 different responses to mastitis infection: (I) overall response, (II) early stage response, (III) late stage response, and (IV) cattle-specific response.