The changes in Z scores for the overrepresented motifs under assumption of perturbed regulator modes. The changes in the Z scores are shown in plots with closed triangles along the proportions with which the TF modes of the connections were randomly swapped between positive and negative. This perturbation procedure was repeated ten times with each proportion of 1%, 5%, 10%, 15% and 20% for (a) DAR-FFCs, (b) coherent FFCs and (c) coherent type-1 FFCs. The results show that the Z scores remain at statistically significant levels with mode perturbation of 1% through 20%. The closed circle on each y-axis represents the Z score of the main results (i.e. without perturbation).