Skip to main content

Table 1 Statistical data for feedforward circuits and autoregulation in the real human transcriptional network in comparison with 1000 randomized networks.

From: Transcriptional double-autorepression feedforward circuits act for multicellularity and nervous system development

   Appearance in the real network Appearance in the randomized networks (mean ± s.d.*) Z score P*
Feedforward circuit
(FFC)
Coherent 403774 378991 ± 13650 1.816 P ≈ 0.035
  Incoherent 103468 105296 ± 7675 -0.238 P ≈ 0.406
  Total 507242 484287 ± 13837 1.659 P < 0.05
Autoregulation   41 36.42 ± 2.95 1.551 P ≈ 0.060
  1. The mean, s.d. and P value of each circuit were computed based on the number of appearances in the 1000 randomized connection matrices (see the Methods).