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Table 1 Statistical data for feedforward circuits and autoregulation in the real human transcriptional network in comparison with 1000 randomized networks.

From: Transcriptional double-autorepression feedforward circuits act for multicellularity and nervous system development

  

Appearance in the real network

Appearance in the randomized networks (mean ± s.d.*)

Z score

P*

Feedforward circuit

(FFC)

Coherent

403774

378991 ± 13650

1.816

P ≈ 0.035

 

Incoherent

103468

105296 ± 7675

-0.238

P ≈ 0.406

 

Total

507242

484287 ± 13837

1.659

P < 0.05

Autoregulation

 

41

36.42 ± 2.95

1.551

P ≈ 0.060

  1. The mean, s.d. and P value of each circuit were computed based on the number of appearances in the 1000 randomized connection matrices (see the Methods).
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BMC Genomics

ISSN: 1471-2164

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