Novel DS dosage effects visualised with the web browser. A) SST and TAC1 have been previously reported as acting in a complex. The deregulated profile of these genes correlates was shown here with the fold-change view of the web browser. B) HSPA5 is a novel gene for DS implicated in neurodegeneration which is also a target of the ATF6 TF whose target set was enriched with significant genes. The histogram displays the p-values for this gene in individual studies. C) KANK1, a gene previously related with paternally inherited cerebral palsy, shows a consistent trend of up-regulation in the considered studies as shown with the fold-change view of the web browser.