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Table 4 Novel DS dosage effects

From: Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes

Ensembl HUGO Score Entropy Chromo-some Start
position
End
position
Band CNV
ENSG00000133110 POSTN 8.301 2.437 chr13 38136722 38172981 q13.3 YES
ENSG00000135919 SERPINE2 5.904 3.048 chr2 224839765 224904036 q36.1  
ENSG00000172893 DHCR7 5.883 3.441 chr11 71145457 71159477 q13.4  
ENSG00000135744 AGT 5.467 2.799 chr1 230838269 230850043 q42.2  
ENSG00000159176 CSRP1 5.424 3.136 chr1 201452658 201478584 q32.1  
ENSG00000178695 KCTD12 5.344 2.373 chr13 77454312 77460540 q22.3  
ENSG00000183087 GAS6 5.129 2.904 chr13 114523524 114567046 q34  
ENSG00000164106 SCRG1 5.127 2.728 chr4 174309300 174320617 q34.1  
ENSG00000166923 GREM1 5.073 1.486 chr15 33010175 33026870 q13.3 YES
ENSG00000163754 GYG1 4.933 3.129 chr3 148709128 148745419 q24  
ENSG00000155380 SLC16A1 4.878 2.927 chr1 113454469 113499635 p13.2 YES
ENSG00000166033 HTRA1 4.811 3.101 chr10 124221041 124274424 q26.13 YES
ENSG00000145632 PLK2 4.785 2.811 chr5 57749809 57756087 q11.2  
ENSG00000115380 EFEMP1 4.726 2.257 chr2 56093102 56151274 p16.1  
ENSG00000060237 WNK1 4.637 2.765 chr12 862089 1020618 p13.33 YES
ENSG00000103888 KIAA1199 4.581 0.885 chr15 81071684 81244117 q25.1  
ENSG00000113810 SMC4 4.462 3.372 chr3 160117062 160152750 q25.33  
ENSG00000198356 ASNA1 4.431 3.067 chr19 12848306 12859137 p13.2  
ENSG00000122952 ZWINT 4.415 3.266 chr10 58116989 58121036 q21.1  
ENSG00000157005 SST 4.401 1.954 chr3 187386694 187388187 q27.3  
ENSG00000117519 CNN3 4.384 3.253 chr1 95362507 95392834 p21.3  
ENSG00000107104 KANK1 4.352 2.508 chr9 470291 746105 p24.3 YES
ENSG00000151414 NEK7 4.329 1.848 chr1 198126121 198291550 q31.3  
ENSG00000044574 HSPA5 4.261 3.449 chr9 127997132 128003609 q33.3  
ENSG00000128590 DNAJB9 4.251 3.241 chr7 108210012 108215294 q31.1  
ENSG00000127920 GNG11 4.226 2.747 chr7 93551011 93555831 q21.3  
ENSG00000008083 JARID2 4.161 3.203 chr6 15246527 15522253 p22.3  
ENSG00000119938 PPP1R3C 4.159 3.036 chr10 93388199 93392858 q23.32  
ENSG00000049245 VAMP3 4.146 3.036 chr1 7831329 7841492 p36.23  
ENSG00000120694 HSPH1 4.129 3.310 chr13 31710762 31736502 q12.3  
ENSG00000168214 RBPJ 4.127 3.291 chr4 26321332 26436753 p15.2  
ENSG00000162909 CAPN2 4.111 3.020 chr1 223889347 223963720 q41 YES
ENSG00000166147 FBN1 4.106 2.070 chr15 48700505 48937918 q21.1 YES
ENSG00000100941 PNN 4.081 3.380 chr14 39644425 39652422 q21.1  
ENSG00000132640 BTBD3 4.074 3.478 chr20 11871371 11907257 p12.2 YES
ENSG00000128708 HAT1 4.064 3.158 chr2 172778958 172848599 q31.1 YES
ENSG00000176105 YES1 4.047 2.855 chr18 721588 812327 p11.32  
ENSG00000152377 SPOCK1 4.025 3.083 chr5 136310987 136835037 q31.2  
ENSG00000136026 CKAP4 4.018 2.754 chr12 106631659 106641908 q23.3  
ENSG00000198121 LPAR1 3.979 2.858 chr9 113635543 113800738 q31.3  
ENSG00000140443 IGF1R 3.951 3.376 chr15 99192200 99507759 q26.3  
ENSG00000198730 CTR9 3.891 3.310 chr11 10772803 10801287 p15.3  
ENSG00000162616 DNAJB4 3.869 3.035 chr1 78444859 78483648 p31.1  
ENSG00000104332 SFRP1 3.825 2.587 chr8 41119483 41166992 p11.21  
ENSG00000116473 RAP1A 3.824 2.769 chr1 112084840 112259313 p13.2  
ENSG00000172500 FIBP 3.804 3.309 chr11 65651211 65656010 q13.1 YES
ENSG00000133703 KRAS 3.801 3.338 chr12 25358182 25403854 p12.1  
ENSG00000163032 VSNL1 3.798 3.099 chr2 17720393 17838285 p24.2  
ENSG00000134684 YARS 3.765 3.431 chr1 33240840 33283754 p35.1  
ENSG00000105854 PON2 3.764 2.862 chr7 95034179 95064510 q21.3  
ENSG00000148943 LIN7C 3.763 3.033 chr11 27516124 27528303 p14.1  
ENSG00000162734 PEA15 3.747 3.418 chr1 160175127 160185166 q23.2  
ENSG00000103187 COTL1 3.731 3.304 chr16 84599200 84651683 q24.1 YES
ENSG00000198648 STK39 3.722 3.439 chr2 168810530 169104651 q24.3  
ENSG00000100577 GSTZ1 3.713 2.759 chr14 77787230 77797939 q24.3  
ENSG00000080371 RAB21 3.707 3.312 chr12 72148658 72181150 q21.1 YES
ENSG00000136108 CKAP2 3.688 2.960 chr13 53029495 53050485 q14.3  
ENSG00000066583 ISOC1 3.686 2.655 chr5 128430442 128449721 q23.3  
ENSG00000143420 ENSA 3.681 3.276 chr1 150573327 150602098 q21.3  
ENSG00000114353 GNAI2 3.680 3.138 chr3 50263724 50296787 p21.31 YES
ENSG00000140105 WARS 3.671 2.994 chr14 100800125 100842680 q32.2  
ENSG00000018625 ATP1A2 3.670 2.733 chr1 160085549 160113381 q23.2