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Table 2 Apolar metabolites significantly affected by TCDD (p < 0.01) and average fold change ratio between treatments (TCDD vs. DMSO).

From: An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

GC-MS Ratio TCDD/DMSO (RTD)
C12:0 0.78
C14:0 0.72
C14:1a 0.70
C14:1b 0.29
C16:1 (n-6) 0.63
C16:1 (n-9) 0.62
C17:0 1.20
C18:0 1.27
C18:1 (n-9) 0.78
C18:1c 0.72
C18:2a 0.71
C18:2b 0.63
C18:2c 1.29
C18:2d 0.64
C18:2e 0.63
C20:1b 0.79
C20:2a 0.74
C20:2b 0.70
C20:3a 0.80
C20:3b 0.64
C22:2 0.61
C22:3a 0.73
1H NMR Ratio TCDD/DMSO (RTD)
Total triglycerides 0.51
Total cholesterol ester 0.69
  1. *Underscore letters indicate isomers (unidentified).
  2. Individual passage number results are in Additional File 1 (Tables S3 and S4).