Table 2 Liver transcripts corresponding to the top 100 most significant features exhibiting differential expression between family groups
Accession or probe number | Gene | Lean/Fat | ANOVA p-value | |
|---|---|---|---|---|
| Â | Â | FO | VO | Â |
Metabolism | ||||
Lipid metabolism | ||||
CK889835 | N-acylethanolamine-hydrolyzing acid amidase precursor | - 1.4 | - 1.2 | 0.0001 |
can_Apo_S1A12 | Apolipoprotein B | - 1.4 | - 1.1 | 0.0014 |
BM414066 | Endothelial lipase precursor | - 1.1 | - 1.6 | 0.0015 |
CK898924 | Lipid phosphate phosphohydrolase 2 | - 1.2 | - 1.2 | 0.0017 |
AJ425826 | Intestinal fatty acid binding protein | 1.1 | 1.2 | 0.0032 |
CO470953 | 1-acyl-sn-glycerol-3-phosphate acyltransferase | - 1.1 | - 1.3 | 0.0040 |
Energy metabolism/generation of precursor metabolites | ||||
EG649459 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex | 1.2 | 1.2 | 0.0009 |
Protein and amino acid metabolism | ||||
CK900470 | 26S protease regulatory subunit 7 | - 1.1 | - 1.2 | 0.0020 |
mus_mfo_15B08 | Proteasome subunit alpha type-1 | 1.2 | 1.1 | 0.0021 |
EG648604 | Serine protease-like protein | 1.0 | 1.4 | 0.0023 |
CO470297 | Transmembrane protease, serine 2 | - 1.2 | - 1.1 | 0.0032 |
DW592216 | Ubiquitin carboxyl-terminal hydrolase 5 | - 1.1 | - 1.1 | 0.0040 |
Transport/intracellular trafficking | ||||
CK886667 | Na/K ATPase | 1.1 | 1.6 | <0.0001 |
CK884193 | Polycystin-2 (Polycystic kidney disease 2 protein homolog) | 1.1 | 1.2 | 0.0002 |
CK890974 | Mitochondrial solute carrier family 25 member 25 | - 1.2 | - 2.2 | 0.0002 |
CK896189 | Mitochondrial solute carrier family 25 member 25 | - 1.3 | - 2.3 | 0.0002 |
CK880187 | ATP-binding cassette sub-family B member 8, mitochondrial | - 1.3 | - 1.1 | 0.0011 |
Regulation of transcription | ||||
CK881770 | Hematopoietically-expressed homeobox protein | - 1.1 | - 1.6 | 0.0001 |
CK888834 | BTEB transcription factor | - 1.4 | - 1.5 | 0.0002 |
CK895950 | Transcription factor CP2-like | - 1.2 | - 1.6 | 0.0010 |
CK884953 | Nuclear transcription factor Y subunit beta | - 1.2 | - 1.1 | 0.0015 |
CK888548 | Rev protein - Human immunodeficiency virus 1 | - 1.5 | - 1.0 | 0.0019 |
CK883410 | Retinoic acid receptor gamma (nuclear receptor) | - 1.1 | - 1.1 | 0.0020 |
int_rpk_78B12 | Sp3 transcription factor | - 1.1 | - 1.4 | 0.0035 |
CK876044 | Homeobox protein HoxB13 | - 1.2 | - 1.2 | 0.0041 |
DW589427 | Cullin-associated and neddylation-dissociated 1 (CAND1) | 1.4 | 1.1 | 0.0044 |
Translation | ||||
AJ424434 | Ribosome production factor 1 | 1.1 | 1.2 | 0.0002 |
gil_oss_G6P11 | 40S ribosomal protein S23 | 1.3 | 1.3 | 0.0008 |
EG648403 | 60S ribosomal protein L7a | 1.2 | 1.2 | 0.0013 |
CK893177 | 40S ribosomal protein S26 | 1.1 | 1.2 | 0.0013 |
DW591137 | 40S ribosomal protein S3a | - 1.2 | - 1.1 | 0.0024 |
EG647811 | 60S ribosomal protein L7 | 1.1 | 1.1 | 0.0026 |
EG648956 | Eukaryotic translation initiation factor 1A | 1.1 | 1.1 | 0.0033 |
AJ424851 | 40S ribosomal protein S18 | 1.2 | 1.2 | 0.0034 |
Signalling/Signal transduction | ||||
CK884714 | 14-3-3 protein epsilon | 1.1 | 1.1 | 0.0003 |
EG648400 | Guanine nucleotide binding protein (G protein) | - 1.2 | - 1.2 | 0.0004 |
CK888542 | Insulin-like growth factor binding protein 1 | - 1.2 | - 2.5 | 0.0008 |
CK886572 | GSK-3-binding protein putative | - 1.1 | 1.8 | 0.0009 |
CK877143 | Calpain-1 | - 1.1 | - 1.4 | 0.0010 |
EG648399 | PTC7 protein phosphatase homolog | - 1.2 | - 1.1 | 0.0016 |
EG648333 | Stathmin | 1.1 | 1.2 | 0.0018 |
CK898969 | G-protein coupled receptor 37 | - 1.1 | - 1.1 | 0.0019 |
DW589782 | Amyloid beta (A4) precursor-like protein | 1.1 | 1.2 | 0.0034 |
CK898590 | Mitogen-activated protein kinase kinase 4 | - 1.0 | - 1.2 | 0.0035 |
CK897997 | Calpastatin | - 1.1 | - 1.1 | 0.0039 |
AJ424385 | Protein tyrosine phosphatase, receptor-type, zeta1 | - 1.1 | - 1.2 | 0.0041 |
Structural proteins | ||||
AJ425204 | Tropomyosin-1 alpha (muscle contraction) | - 1.1 | - 1.2 | 0.0031 |
Immune response | ||||
CK886548 | T cell receptor (TCR)-alpha/delta locus | - 1.1 | - 1.2 | 0.0005 |
CK894741 | Complement factor D (adapsin) | - 1.1 | - 1.2 | 0.0007 |
AM042439 | Major histocompatibility complex (MHC) class I antigene | - 1.3 | - 1.4 | 0.0014 |
kid_cki_A1G02 | Interferon-inducible protein | - 1.2 | - 1.4 | 0.0015 |
CO471904 | Major histocompatability complex (MHCI) | - 1.1 | - 1.2 | 0.0019 |
CK894557 | Major histocompatability complex (MHCI) | - 1.2 | - 1.1 | 0.0023 |
AM042249 | Major histocompatability complex (MHCI) | - 1.1 | - 1.2 | 0.0025 |
bra_opk_01B08 | Scavenger receptor cysteine-rich gene | - 1.3 | - 1.6 | 0.0029 |
CO469739 | T-cell receptor(TCR)-alpha/delta locus | - 1.1 | - 1.1 | 0.0030 |
AJ424124 | Major histocompatibility complex (MHC class I) | - 1.2 | - 1.1 | 0.0037 |
hrt_opk_07E23 | Interferon alpha 1-like | - 1.1 | - 1.1 | 0.0041 |
Miscellaneous and unknown function | ||||
CK898014 | Protein fuzzy homolog | - 1.1 | - 1.2 | 0.0002 |
kid_cki_A2A05 | Cyclin B2 | - 1.3 | - 1.4 | 0.0006 |
EG647643 | Purine nucleoside phosphorylase | - 1.1 | - 2.0 | 0.0010 |
liv_lrr_07B04 | Nuclear protein 1 | - 1.1 | - 2.1 | 0.0028 |
AM402622 | Non-POU domain containing, octamer-binding | - 1.7 | - 1.4 | 0.0029 |
EG648147 | Adhesion-regulating molecule 1 | - 1.2 | - 1.1 | 0.0037 |
BM414485 | Apoptosis-inducing factor mitochondrion-associated inducer | 1.4 | 1.5 | 0.0038 |
DW589496 | Cyclin-dependent kinase inhibitor | - 1.2 | - 1.3 | 0.0044 |