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Figure 1 | BMC Genomics

Figure 1

From: Modeling the asymmetric evolution of a mouse and rat-specific microRNA gene cluster intron 10 of the Sfmbt2 gene

Figure 1

C2MC is a large miRNA cluster in intron 10 of the Sfmbt2 gene. Overview of the mouse Polycomb group gene Sfmbt2 is shown using the mouse UCSC genome browser (Version mm9 - http://genome.ucsc.edu). A) All miRNA genes are present inside a ~54 Kb region of Sfmbt2 intron 10, which is not conserved in other mammals except to some extent for rat (Chr2: 10,285,001-10,525,000). B) The cluster contains 65 miRNA genes and is flanked by conserved parts of intron 10 (Chr2: 10,385,001-10,441,000). C) The centrally located miRNA genes appear evenly spaced. The cluster's compartmentalized organization is indicated by multiple mappings of RefSeq Genes and by its repeating element content (Chr2: 10,418,831-10,424,030).

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BMC Genomics

ISSN: 1471-2164

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