Figure 3

The enrichment of p300 binding sites around mouse orthologs of human ST miRNAs. Figure 3 shows the cumulative curves of the enhancer enrichment analysis using all p300 binding sites (A) and using only p300 binding sites that do not overlap HCNEs conserved between human and mouse (percentage of identity ≥ 98% and length of HCNE ≥ 50 bp) (B). These results indicate that the mouse orthologs of human ST miRNAs are more likely to be located in regions with significantly higher p300 binding site density than the control set of protein coding and non-coding regions.