Genomic features and computational identification of human microRNAs under long-range developmental regulation

BMC Genomics

Table 2 Comparison of CpG-to-gene ratios between different gene sets

	HCNE enriched miRNAs	HCNE poor miRNAs	Known GRB target genes	Known bystander genes	Other transcription factors	Other CpG island genes
Median CpG-to-gene ratio	0.1703	0.0238	0.2032	0.0100	0.0339	0.0280
p-values:
HCNE enriched miRNAs	-	0.2931	0.1185	2.7450e-4	0.0124	2.7800e-3
HCNE poor miRNAs	0.2931	-	0.0158	0.1846	0.0966	1.4200e-3

Significant differences in the median CpG-to-gene ratio between the gene sets were determined using the two-sided bootstrapped version of the Kolmogorov-Smirnov test. Significant p-values (<0.05) are shown in bold. The first row indicates the median CpG-to-gene ratio for each gene set and the second and third rows contain the p-values of the comparisons between the CpG-to-gene ratios of the HCNE enriched or HCNE poor ST miRNAs and other control gene sets.

ISSN: 1471-2164